Cargando...

Tracking and transforming neocortical progenitors by CRISPR/Cas9 gene targeting and piggyBac transposase lineage labeling

The ability to induce targeted mutations in somatic cells in developing organisms and then track the fates of those cells is a powerful approach both for studying neural development and for modeling human disease. The CRISPR/Cas9 system allows for such targeted mutagenesis, and we therefore tested i...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Development
Main Authors: Chen, Fuyi, Rosiene, Joel, Che, Alicia, Becker, Albert, LoTurco, Joseph
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631763/
https://ncbi.nlm.nih.gov/pubmed/26400094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.118836
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!