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Hydroxyl Radical Dosimetry for High Flux Hydroxyl Radical Protein Footprinting Applications Using a Simple Optical Detection Method

Hydroxyl radical protein footprinting (HRPF) by Fast Photochemical Oxidation of Proteins (FPOP) is a powerful benchtop tool used to probe protein structure, interactions, and conformational changes in solution. However, the reproducibility of all HRPF techniques is limited by the ability to deliver...

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Publicat a:Anal Chem
Autors principals: Xie, Boer, Sharp, Joshua S.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631671/
https://ncbi.nlm.nih.gov/pubmed/26455423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.5b02865
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