Activation of serotonin 5-HT(2C) receptor suppresses behavioral sensitization and naloxone-precipitated withdrawal symptoms in heroin-treated mice

Abuse and dependence to heroin has evolved into a global epidemic as a significant clinical and societal problem with devastating consequences. Repeated exposure to heroin can induce long-lasting behavioral sensitization and withdrawal. Pharmacological activation of 5-HT(2C) receptors (5-HT(2C)Rs) s...

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Udgivet i:Neurosci Lett
Main Authors: Wu, Xian, Pang, Gang, Zhang, Yong-Mei, Li, Guangwu, Xu, Shengchun, Dong, Liuyi, Stackman, Robert W., Zhang, Gongliang
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631619/
https://ncbi.nlm.nih.gov/pubmed/26375926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2015.09.013
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