Activation of serotonin 5-HT(2C) receptor suppresses behavioral sensitization and naloxone-precipitated withdrawal symptoms in morphine-dependent mice

Opioid abuse and dependence have evolved into an international epidemic as a significant clinical and social problem with devastating consequences. Repeated exposure to the opioid, for example morphine, can induce profound, long-lasting behavioral sensitization and physical dependence, which are tho...

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Udgivet i:Neuropharmacology
Main Authors: Zhang, Gongliang, Wu, Xian, Zhang, Yong-Mei, Liu, Huan, Jiang, Qin, Pang, Gang, Tao, Xinrong, Dong, Liuyi, Stackman, Robert W.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996259/
https://ncbi.nlm.nih.gov/pubmed/26432939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2015.09.031
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