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V(H)DJ(H) Gene Sequences and Antigen Reactivity of Monoclonal Antibodies Produced by Human B-1 Cells: Evidence for Somatic Selection(,)
To understand whether the distinct V(H)DJ(H) gene utilization by natural polyreactive Abs reflects the developmentally restricted Ig V(H)DJ(H) rearrangements putatively expressed by B-1 cells, we generated 11 (8 IgM, 1 IgG3, 2 IgA1), 7 (6 IgM, 1 IgG1), and 7 (2 IgM, 3 IgG1, 2 IgG3) mAb-producing lin...
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| Publicat a: | J Immunol |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4631314/ https://ncbi.nlm.nih.gov/pubmed/9037000 |
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