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Endogenous antigen processing drives the primary CD4(+) T cell response to influenza

By convention, CD4(+) T lymphocytes recognize foreign and self peptides derived from internalized antigens in combination with MHC class II molecules. Alternative pathways of epitope production have been identified but their contributions to host defense have not been established. We show here in a...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Miller, Michael A., Ganesan, Asha Purnima V., Luckashenak, Nancy, Mendonca, Mark, Eisenlohr, Laurence C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629989/
https://ncbi.nlm.nih.gov/pubmed/26413780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3958
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