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Smooth muscle cell progenitors are primed to muscularize in pulmonary hypertension

Excess and ectopic smooth muscle cells (SMCs) are central to cardiovascular disease pathogenesis, but underlying mechanisms are poorly defined. For instance, pulmonary hypertension (PH) or elevated pulmonary artery blood pressure is a devastating disease with distal extension of smooth muscle to nor...

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Détails bibliographiques
Publié dans:Sci Transl Med
Auteurs principaux: Sheikh, Abdul Q., Misra, Ashish, Rosas, Ivan O., Adams, Ralf H., Greif, Daniel M.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629985/
https://ncbi.nlm.nih.gov/pubmed/26446956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa9712
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