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Smooth muscle cell progenitors are primed to muscularize in pulmonary hypertension

Excess and ectopic smooth muscle cells (SMCs) are central to cardiovascular disease pathogenesis, but underlying mechanisms are poorly defined. For instance, pulmonary hypertension (PH) or elevated pulmonary artery blood pressure is a devastating disease with distal extension of smooth muscle to nor...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Sheikh, Abdul Q., Misra, Ashish, Rosas, Ivan O., Adams, Ralf H., Greif, Daniel M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629985/
https://ncbi.nlm.nih.gov/pubmed/26446956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaa9712
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