MURC deficiency in smooth muscle attenuates pulmonary hypertension

Emerging evidence suggests that caveolin-1 (Cav1) is associated with pulmonary arterial hypertension. MURC (also called Cavin-4) is a member of the cavin family, which regulates caveolar formation and functions together with caveolins. Here, we show that hypoxia increased Murc mRNA expression in the...

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Vydáno v:Nat Commun
Hlavní autoři: Nakanishi, Naohiko, Ogata, Takehiro, Naito, Daisuke, Miyagawa, Kotaro, Taniguchi, Takuya, Hamaoka, Tetsuro, Maruyama, Naoki, Kasahara, Takeru, Nishi, Masahiro, Matoba, Satoaki, Ueyama, Tomomi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996946/
https://ncbi.nlm.nih.gov/pubmed/27546070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12417
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