Integrin beta3 regulates clonality and fate of smooth muscle-derived atherosclerotic plaque cells

Smooth muscle cells (SMCs) play a key role in atherogenesis. However, mechanisms regulating expansion and fate of pre-existing SMCs in atherosclerotic plaques remain poorly defined. Here we show that multiple SMC progenitors mix to form the aorta during development. In contrast, during atherogenesis...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Misra, Ashish, Feng, Zhonghui, Chandran, Rachana R., Kabir, Inamul, Rotllan, Noemi, Aryal, Binod, Sheikh, Abdul Q., Ding, Ling, Qin, Lingfeng, Fernández-Hernando, Carlos, Tellides, George, Greif, Daniel M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970166/
https://ncbi.nlm.nih.gov/pubmed/29802249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04447-7
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