A Synthetic Aptamer-Drug Adduct for Targeted Liver Cancer Therapy

AS1411 (previously known as AGRO100) is a 26 nucleotide guanine-rich DNA aptamer which forms a guanine quadruplex structure. AS1411 has shown promising utility as a treatment for cancers in Phase I and Phase II clinical trials without causing major side-effects. AS1411 inhibits tumor cell growth by...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Trinh, Thu Le, Zhu, Guizhi, Xiao, Xilin, Puszyk, William, Sefah, Kwame, Wu, Qunfeng, Tan, Weihong, Liu, Chen
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629891/
https://ncbi.nlm.nih.gov/pubmed/26523833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136673
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker