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Dialkyl Ether Formation via Nickel-Catalyzed Cross Coupling of Acetals and Aryl Iodides()

A new substrate class for Ni-catalyzed C(sp(3)) cross-coupling reactions is reported. We show that α-oxy radicals generated from abundant and stable benzylic acetals, TMSCl, and a mild reductant can participate in chemoselective cross coupling with aryl iodides and a vinyl triflate using a 2,6-bis(N...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Arendt, Kevin M., Doyle, Abigail G.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629785/
https://ncbi.nlm.nih.gov/pubmed/26219537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201503936
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