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E1 of α-ketoglutarate dehydrogenase defends Mycobacterium tuberculosis against glutamate anaplerosis and nitroxidative stress

Enzymes of central carbon metabolism (CCM) in Mycobacterium tuberculosis (Mtb) make an important contribution to the pathogen’s virulence. Evidence is emerging that some of these enzymes are not simply playing the metabolic roles for which they are annotated, but can protect the pathogen via additio...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Maksymiuk, Christina, Balakrishnan, Anand, Bryk, Ruslana, Rhee, Kyu Y., Nathan, Carl F.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629369/
https://ncbi.nlm.nih.gov/pubmed/26430237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510932112
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