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Establishment of drug-resistant HBV small-animal models by hydrodynamic injection
In antiviral therapy of hepatitis B virus (HBV) infection, drug resistance remains a huge obstacle to the long-term effectiveness of nucleoside/tide analogs (NAs). Primary resistance mutation (rtM204V) contributes to lamivudine (LAM)-resistance, and compensatory mutations (rtL180M and rtV173L) resto...
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| Publicado no: | Acta Pharm Sin B |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4629082/ https://ncbi.nlm.nih.gov/pubmed/26579395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2014.06.009 |
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