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T cell--associated immunoregulation and antiviral effect of oxymatrine in hydrodynamic injection HBV mouse model

Although oxymatrine (OMT) has been shown to directly inhibit the replication of hepatitis B virus (HBV) in vitro, limited research has been done with this drug in vivo. In the present study, the antiviral effect of OMT was investigated in an immunocompetent mouse model of chronic HBV infection. The...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Sang, Xiuxiu, Wang, Ruilin, Han, Yanzhong, Zhang, Cong'en, Shen, Honghui, Yang, Zhirui, Xiong, Yin, Liu, Huimin, Liu, Shijing, Li, Ruisheng, Yang, Ruichuang, Wang, Jiabo, Wang, Xuejun, Bai, Zhaofang, Xiao, Xiaohe
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430867/
https://ncbi.nlm.nih.gov/pubmed/28540167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2017.02.005
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