High-fat diet amplifies renal renin angiotensin system expression, blood pressure elevation, and renal dysfunction caused by Ceacam1 null deletion

Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAMl), a substrate of the insulin receptor tyrosine kinase, regulates insulin action by promoting insulin clearance. Global null mutation of Ceacam1 gene (Cc1(−/−)) results in features of the metabolic syndrome, including insulin resistan...

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Bibliografske podrobnosti
izdano v:Am J Physiol Endocrinol Metab
Main Authors: Li, Caixia, Culver, Silas A., Quadri, Syed, Ledford, Kelly L., Al-Share, Qusai Y., Ghadieh, Hilda E., Najjar, Sonia M., Siragy, Helmy M.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2015
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628940/
https://ncbi.nlm.nih.gov/pubmed/26374765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00158.2015
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