Potent functional immunogenicity of Plasmodium falciparum transmission-blocking antigen (Pfs25) delivered with nanoemulsion and porous polymeric nanoparticles

PURPOSE: To evaluate functional immunogenicity of CHrPfs25. a malaria transmission blocking vaccine antigen, using nanoemulsion and porous polymeric PLGA nanoparticles. METHODS: CHrPfs25 was formulated with nanoemulsions (NE) and poly(D,L-lactide-co-glycolide) nanoparticles (PLGA-NP) and evaluated v...

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Udgivet i:Pharm Res
Main Authors: Kumar, Rajesh, Ledet, Grace, Graves, Richard, Datta, Dibyadyuti, Robinson, Shana, Bansal, Geetha P., Mandal, Tarun, Kumar, Nirbhay
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628851/
https://ncbi.nlm.nih.gov/pubmed/26113235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-015-1743-x
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