Dual Mutation Events in the Haemagglutinin-Esterase and Fusion Protein from an Infectious Salmon Anaemia Virus HPR0 Genotype Promote Viral Fusion and Activation by an Ubiquitous Host Protease

In Infectious salmon anaemia virus (ISAV), deletions in the highly polymorphic region (HPR) in the near membrane domain of the haemagglutinin-esterase (HE) stalk, influence viral fusion. It is suspected that selected mutations in the associated Fusion (F) protein may also be important in regulating...

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Publicado en:PLoS One
Autores principales: Fourrier, Mickael, Lester, Katherine, Markussen, Turhan, Falk, Knut, Secombes, Christopher J., McBeath, Alastair, Collet, Bertrand
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627773/
https://ncbi.nlm.nih.gov/pubmed/26517828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142020
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