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Dual Mutation Events in the Haemagglutinin-Esterase and Fusion Protein from an Infectious Salmon Anaemia Virus HPR0 Genotype Promote Viral Fusion and Activation by an Ubiquitous Host Protease

In Infectious salmon anaemia virus (ISAV), deletions in the highly polymorphic region (HPR) in the near membrane domain of the haemagglutinin-esterase (HE) stalk, influence viral fusion. It is suspected that selected mutations in the associated Fusion (F) protein may also be important in regulating...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Fourrier, Mickael, Lester, Katherine, Markussen, Turhan, Falk, Knut, Secombes, Christopher J., McBeath, Alastair, Collet, Bertrand
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627773/
https://ncbi.nlm.nih.gov/pubmed/26517828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142020
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