CAR Suppresses Hepatic Gluconeogenesis by Facilitating the Ubiquitination and Degradation of PGC1α

The constitutive androstane receptor (CAR) and peroxisome proliferator-activated receptor gamma coactivator-1α (PGC1α) are master regulators of drug metabolism and gluconeogenesis, respectively. In supporting the cross talk between drug metabolism and energy metabolism, activation of CAR has been sh...

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Bibliografiska uppgifter
I publikationen:Mol Endocrinol
Huvudupphovsmän: Gao, Jie, Yan, Jiong, Xu, Meishu, Ren, Songrong, Xie, Wen
Materialtyp: Artigo
Språk:Inglês
Publicerad: Endocrine Society 2015
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627603/
https://ncbi.nlm.nih.gov/pubmed/26407237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1145
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