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Investigation of the interactions between the EphB2 receptor and SNEW peptide variants

EphB2 interacts with cell surface-bound ephrin ligands to relay bidirectional signals. Overexpression of the EphB2 receptor protein has been linked to different types of cancer. The SNEW (SNEWIQPRLPQH) peptide binds with high selectivity and moderate affinity to EphB2, inhibiting Eph-ephrin interact...

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Библиографические подробности
Опубликовано в: :Growth Factors
Главные авторы: Ma, Buyong, Kolb, Stephanie, Diprima, Michael, Karna, Molleshree, Tosato, Giovanna, Yang, Qiqi, Huang, Qiang, Nussinov, Ruth
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627370/
https://ncbi.nlm.nih.gov/pubmed/25410963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08977194.2014.985786
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