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Investigation of the interactions between the EphB2 receptor and SNEW peptide variants

EphB2 interacts with cell surface-bound ephrin ligands to relay bidirectional signals. Overexpression of the EphB2 receptor protein has been linked to different types of cancer. The SNEW (SNEWIQPRLPQH) peptide binds with high selectivity and moderate affinity to EphB2, inhibiting Eph-ephrin interact...

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Publicat a:Growth Factors
Autors principals: Ma, Buyong, Kolb, Stephanie, Diprima, Michael, Karna, Molleshree, Tosato, Giovanna, Yang, Qiqi, Huang, Qiang, Nussinov, Ruth
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627370/
https://ncbi.nlm.nih.gov/pubmed/25410963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08977194.2014.985786
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