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Investigation of the interactions between the EphB2 receptor and SNEW peptide variants

EphB2 interacts with cell surface-bound ephrin ligands to relay bidirectional signals. Overexpression of the EphB2 receptor protein has been linked to different types of cancer. The SNEW (SNEWIQPRLPQH) peptide binds with high selectivity and moderate affinity to EphB2, inhibiting Eph-ephrin interact...

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Dettagli Bibliografici
Pubblicato in:Growth Factors
Autori principali: Ma, Buyong, Kolb, Stephanie, Diprima, Michael, Karna, Molleshree, Tosato, Giovanna, Yang, Qiqi, Huang, Qiang, Nussinov, Ruth
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627370/
https://ncbi.nlm.nih.gov/pubmed/25410963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08977194.2014.985786
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