RhoE is required for contact inhibition and negatively regulates tumor initiation and progression

RhoE is a small GTPase involved in the regulation of actin cytoskeleton dynamics, cell cycle and apoptosis. The role of RhoE in cancer is currently controversial, with reports of both oncogenic and tumor-suppressive functions for RhoE. Using RhoE-deficient mice, we show here that the absence of RhoE...

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Publicado en:Oncotarget
Autores principales: Hernández-Sánchez, Marta, Poch, Enric, Guasch, Rosa M., Ortega, Joaquín, López-Almela, Inmaculada, Palmero, Ignacio, Pérez-Roger, Ignacio
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627322/
https://ncbi.nlm.nih.gov/pubmed/26036260
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