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RhoE Deficiency Produces Postnatal Lethality, Profound Motor Deficits and Neurodevelopmental Delay in Mice

Rnd proteins are a subfamily of Rho GTPases involved in the control of actin cytoskeleton dynamics and other cell functions such as motility, proliferation and survival. Unlike other members of the Rho family, Rnd proteins lack GTPase activity and therefore remain constitutively active. We have rece...

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Detalhes bibliográficos
Main Authors: Mocholí, Enric, Ballester-Lurbe, Begoña, Arqué, Gloria, Poch, Enric, Peris, Blanca, Guerri, Consuelo, Dierssen, Mara, Guasch, Rosa M., Terrado, José, Pérez-Roger, Ignacio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084285/
https://ncbi.nlm.nih.gov/pubmed/21552537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019236
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