RhoE Deficiency Produces Postnatal Lethality, Profound Motor Deficits and Neurodevelopmental Delay in Mice

Rnd proteins are a subfamily of Rho GTPases involved in the control of actin cytoskeleton dynamics and other cell functions such as motility, proliferation and survival. Unlike other members of the Rho family, Rnd proteins lack GTPase activity and therefore remain constitutively active. We have rece...

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Main Authors: Mocholí, Enric, Ballester-Lurbe, Begoña, Arqué, Gloria, Poch, Enric, Peris, Blanca, Guerri, Consuelo, Dierssen, Mara, Guasch, Rosa M., Terrado, José, Pérez-Roger, Ignacio
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084285/
https://ncbi.nlm.nih.gov/pubmed/21552537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019236
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