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TRPM8 channel as a novel molecular target in androgen-regulated prostate cancer cells

The cold and menthol receptor TRPM8 is highly expressed in prostate and prostate cancer (PC). Recently, we identified that TRPM8 is as an ionotropic testosterone receptor. The TRPM8 mRNA is expressed in early prostate tumors with high androgen levels, while anti-androgen therapy greatly reduces its...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Asuthkar, Swapna, Velpula, Kiran Kumar, Elustondo, Pia A., Demirkhanyan, Lusine, Zakharian, Eleonora
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627303/
https://ncbi.nlm.nih.gov/pubmed/25980497
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