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TRPM8 channel as a novel molecular target in androgen-regulated prostate cancer cells

The cold and menthol receptor TRPM8 is highly expressed in prostate and prostate cancer (PC). Recently, we identified that TRPM8 is as an ionotropic testosterone receptor. The TRPM8 mRNA is expressed in early prostate tumors with high androgen levels, while anti-androgen therapy greatly reduces its...

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Publicat a:Oncotarget
Autors principals: Asuthkar, Swapna, Velpula, Kiran Kumar, Elustondo, Pia A., Demirkhanyan, Lusine, Zakharian, Eleonora
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627303/
https://ncbi.nlm.nih.gov/pubmed/25980497
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