Beyond the one-locus-one-miRNA paradigm: microRNA isoforms enable deeper insights into breast cancer heterogeneity

Here we describe our study of miRNA isoforms (isomiRs) in breast cancer (BRCA) and normal breast data sets from the Cancer Genome Atlas (TCGA) repository. We report that the full isomiR profiles, from both known and novel human-specific miRNA loci, are particularly rich in information and can distin...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Telonis, Aristeidis G., Loher, Phillipe, Jing, Yi, Londin, Eric, Rigoutsos, Isidore
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2015
Konular:
Computational Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627084/
https://ncbi.nlm.nih.gov/pubmed/26400174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv922
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