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A structural approach reveals how neighbouring C2H2 zinc fingers influence DNA binding specificity

Development of an accurate protein–DNA recognition code that can predict DNA specificity from protein sequence is a central problem in biology. C(2)H(2) zinc fingers constitute by far the largest family of DNA binding domains and their binding specificity has been studied intensively. However, despi...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Garton, Michael, Najafabadi, Hamed S., Schmitges, Frank W., Radovani, Ernest, Hughes, Timothy R., Kim, Philip M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627083/
https://ncbi.nlm.nih.gov/pubmed/26384429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv919
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