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A PTEN translational isoform has PTEN-like activity

BACKGROUND: To identify PTEN isoform and explore its potential role in tumor suppression. METHODS: Western blotting, over-expression, shRNA mediated knocking-down, and bioinformatic analysis were used to identify PTEN isoform and test its effect on PI3K-Akt signaling pathway. Cell proliferation, apo...

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Publicado en:Chin J Cancer Res
Autores principales: Zhang, Xie, Yin, Bowei, Zhu, Fangfang, Huang, Guochang, Li, Hong
Formato: Artigo
Lenguaje:Inglês
Publicado: AME Publishing Company 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626823/
https://ncbi.nlm.nih.gov/pubmed/26543340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.1000-9604.2015.10.03
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