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A PTEN translational isoform has PTEN-like activity
BACKGROUND: To identify PTEN isoform and explore its potential role in tumor suppression. METHODS: Western blotting, over-expression, shRNA mediated knocking-down, and bioinformatic analysis were used to identify PTEN isoform and test its effect on PI3K-Akt signaling pathway. Cell proliferation, apo...
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Publicado en: | Chin J Cancer Res |
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Autores principales: | , , , , |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
AME Publishing Company
2015
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4626823/ https://ncbi.nlm.nih.gov/pubmed/26543340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.1000-9604.2015.10.03 |
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