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The evolution of tumor metastasis during clonal expansion with alterations in metastasis driver genes
Metastasis is a leading cause of cancer-related deaths. Carcinoma generally initiates at a specific organ as a primary tumor, but eventually metastasizes and forms tumor sites in other organs. In this report, we developed a mathematical model of cancer progression with alterations in metastasis-rela...
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Publicado no: | Sci Rep |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4626809/ https://ncbi.nlm.nih.gov/pubmed/26515895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15886 |
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