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Site-Specific Amino Acid Preferences Are Mostly Conserved in Two Closely Related Protein Homologs

Evolution drives changes in a protein’s sequence over time. The extent to which these changes in sequence lead to shifts in the underlying preference for each amino acid at each site is an important question with implications for comparative sequence-analysis methods, such as molecular phylogenetics...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Doud, Michael B., Ashenberg, Orr, Bloom, Jesse D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626756/
https://ncbi.nlm.nih.gov/pubmed/26226986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv167
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