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Effect of acute fentanyl treatment on synaptic plasticity in the hippocampal CA1 region in rats

Postoperative cognitive dysfunction (POCD), mainly characterized by short-term decline of learning and memory, occurs after operations under anesthesia. However, the underlying mechanisms are poorly understood. The μ-opioid receptors (MOR) are highly expressed in interneurons of hippocampus, and is...

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Vydáno v:Front Pharmacol
Hlavní autoři: Tian, Hai, Xu, Yueming, Liu, Fucun, Wang, Guowei, Hu, Sanjue
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626754/
https://ncbi.nlm.nih.gov/pubmed/26578961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00251
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