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Cell Death Inducing Microbial Protein Phosphatase Inhibitors—Mechanisms of Action

Okadaic acid (OA) and microcystin (MC) as well as several other microbial toxins like nodularin and calyculinA are known as tumor promoters as well as inducers of apoptotic cell death. Their intracellular targets are the major serine/threonine protein phosphatases. This review summarizes mechanisms...

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Dettagli Bibliografici
Pubblicato in:Mar Drugs
Autori principali: Kleppe, Rune, Herfindal, Lars, Døskeland, Stein Ove
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626703/
https://ncbi.nlm.nih.gov/pubmed/26506362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13106505
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