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Cell Death Inducing Microbial Protein Phosphatase Inhibitors—Mechanisms of Action

Okadaic acid (OA) and microcystin (MC) as well as several other microbial toxins like nodularin and calyculinA are known as tumor promoters as well as inducers of apoptotic cell death. Their intracellular targets are the major serine/threonine protein phosphatases. This review summarizes mechanisms...

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Détails bibliographiques
Publié dans:Mar Drugs
Auteurs principaux: Kleppe, Rune, Herfindal, Lars, Døskeland, Stein Ove
Format: Artigo
Langue:Inglês
Publié: MDPI 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626703/
https://ncbi.nlm.nih.gov/pubmed/26506362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13106505
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