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The Trigger Factor Chaperone Encapsulates and Stabilizes Partial Folds of Substrate Proteins

How chaperones interact with protein chains to assist in their folding is a central open question in biology. Obtaining atomistic insight is challenging in particular, given the transient nature of the chaperone-substrate complexes and the large system sizes. Recent single-molecule experiments have...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Singhal, Kushagra, Vreede, Jocelyne, Mashaghi, Alireza, Tans, Sander J., Bolhuis, Peter G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626277/
https://ncbi.nlm.nih.gov/pubmed/26512985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004444
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