Activation of sonic hedgehog signaling enhances cell migration and invasion by induction of matrix metalloproteinase-2 and -9 via the phosphoinositide-3 kinase/AKT signaling pathway in glioblastoma

Aberrant hedgehog signaling contributes to the development of various malignancies, including glioblastoma (GBM). However, the potential mechanism of hedgehog signaling in GBM migration and invasion has remained to be elucidated. The present study showed that enhanced hedgehog signaling by recombina...

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Vydáno v:Mol Med Rep
Hlavní autoři: CHANG, LIANG, ZHAO, DAN, LIU, HUI-BIN, WANG, QIU-SHI, ZHANG, PING, LI, CHEN-LONG, DU, WEN-ZHONG, WANG, HONG-JUN, LIU, XING, ZHANG, ZHI-REN, JIANG, CHUAN-LU
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2015
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626128/
https://ncbi.nlm.nih.gov/pubmed/26299938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4229
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