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The Sonic Hedgehog Signaling Pathway Induces Myopic Development by Activating Matrix Metalloproteinase (MMP)-2 in Guinea Pigs

PURPOSE: To investigate whether the Sonic hedgehog (Shh) signaling induces myopic development by increasing the expression of matrix metalloproteinase (MMP)-2 in guinea pigs. METHODS: A translucent diffuser was glued onto the right eye to induce form-deprivation myopia (FDM) in 10 guinea pigs. Four...

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Detalhes bibliográficos
Main Authors: Chen, Minjie, Qian, Yishan, Dai, Jinhui, Chu, Renyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014572/
https://ncbi.nlm.nih.gov/pubmed/24810957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096952
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