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Characterizing selective pressures on the pathway for de novo biosynthesis of pyrimidines in yeast

BACKGROUND: Selection on proteins is typically measured with the assumption that each protein acts independently. However, selection more likely acts at higher levels of biological organization, requiring an integrative view of protein function. Here, we built a kinetic model for de novo pyrimidine...

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Detalles Bibliográficos
Publicado en:BMC Evol Biol
Main Authors: Hermansen, Russell A., Mannakee, Brian K., Knecht, Wolfgang, Liberles, David A., Gutenkunst, Ryan N.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625875/
https://ncbi.nlm.nih.gov/pubmed/26511837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-015-0515-x
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