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Antitumor activity of the multikinase inhibitor regorafenib in patient-derived xenograft models of gastric cancer

BACKGROUND: Unresectable gastric cancer is associated with poor outcomes, with few treatment options available after failure of cytotoxic chemotherapy. Clinical trials of targeted therapies have generally shown no survival benefit in gastric cancer, with the exceptions of the antibodies ramucirumab...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Huynh, Hung, Ong, Richard, Zopf, Dieter
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625870/
https://ncbi.nlm.nih.gov/pubmed/26514182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0243-5
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