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Antitumor activity of the multikinase inhibitor regorafenib in patient-derived xenograft models of gastric cancer

BACKGROUND: Unresectable gastric cancer is associated with poor outcomes, with few treatment options available after failure of cytotoxic chemotherapy. Clinical trials of targeted therapies have generally shown no survival benefit in gastric cancer, with the exceptions of the antibodies ramucirumab...

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Publicado en:J Exp Clin Cancer Res
Autores principales: Huynh, Hung, Ong, Richard, Zopf, Dieter
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625870/
https://ncbi.nlm.nih.gov/pubmed/26514182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0243-5
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