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Antitumor activity of the multikinase inhibitor regorafenib in patient-derived xenograft models of gastric cancer

BACKGROUND: Unresectable gastric cancer is associated with poor outcomes, with few treatment options available after failure of cytotoxic chemotherapy. Clinical trials of targeted therapies have generally shown no survival benefit in gastric cancer, with the exceptions of the antibodies ramucirumab...

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Détails bibliographiques
Publié dans:J Exp Clin Cancer Res
Auteurs principaux: Huynh, Hung, Ong, Richard, Zopf, Dieter
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625870/
https://ncbi.nlm.nih.gov/pubmed/26514182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0243-5
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