Exploring DNA methylation changes in promoter, intragenic, and intergenic regions as early and late events in breast cancer formation

BACKGROUND: Breast cancer formation is associated with frequent changes in DNA methylation but the extent of very early alterations in DNA methylation and the biological significance of cancer-associated epigenetic changes need further elucidation. METHODS: Pyrosequencing was done on bisulfite-treat...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Rauscher, Garth H., Kresovich, Jacob K., Poulin, Matthew, Yan, Liying, Macias, Virgilia, Mahmoud, Abeer M., Al-Alem, Umaima, Kajdacsy-Balla, Andre, Wiley, Elizabeth L., Tonetti, Debra, Ehrlich, Melanie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625569/
https://ncbi.nlm.nih.gov/pubmed/26510686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1777-9
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