BRCA1 protein expression and subcellular localization in primary breast cancer: Automated digital microscopy analysis of tissue microarrays

PURPOSE: Mutations in BRCA1 are associated with familial as well as sporadic aggressive subtypes of breast cancer, but less is known about whether BRCA1 expression or subcellular localization contributes to progression in population-based settings. METHODS: We examined BRCA1 expression and subcellul...

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Publicat a:PLoS One
Autors principals: Mahmoud, Abeer M., Macias, Virgilia, Al-alem, Umaima, Deaton, Ryan J., Kadjaksy-Balla, Andre, Gann, Peter H., Rauscher, Garth H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581176/
https://ncbi.nlm.nih.gov/pubmed/28863181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184385
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