BRCA1 protein expression and subcellular localization in primary breast cancer: Automated digital microscopy analysis of tissue microarrays

PURPOSE: Mutations in BRCA1 are associated with familial as well as sporadic aggressive subtypes of breast cancer, but less is known about whether BRCA1 expression or subcellular localization contributes to progression in population-based settings. METHODS: We examined BRCA1 expression and subcellul...

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Опубликовано в: :PLoS One
Главные авторы: Mahmoud, Abeer M., Macias, Virgilia, Al-alem, Umaima, Deaton, Ryan J., Kadjaksy-Balla, Andre, Gann, Peter H., Rauscher, Garth H.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581176/
https://ncbi.nlm.nih.gov/pubmed/28863181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184385
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