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Extended notions of sign consistency to relate experimental data to signaling and regulatory network topologies

BACKGROUND: A rapidly growing amount of knowledge about signaling and gene regulatory networks is available in databases such as KEGG, Reactome, or RegulonDB. There is an increasing need to relate this knowledge to high-throughput data in order to (in)validate network topologies or to decide which i...

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Pubblicato in:BMC Bioinformatics
Autori principali: Thiele, Sven, Cerone, Luca, Saez-Rodriguez, Julio, Siegel, Anne, Guziołowski, Carito, Klamt, Steffen
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625540/
https://ncbi.nlm.nih.gov/pubmed/26510976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0733-7
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