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Extended notions of sign consistency to relate experimental data to signaling and regulatory network topologies

BACKGROUND: A rapidly growing amount of knowledge about signaling and gene regulatory networks is available in databases such as KEGG, Reactome, or RegulonDB. There is an increasing need to relate this knowledge to high-throughput data in order to (in)validate network topologies or to decide which i...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Thiele, Sven, Cerone, Luca, Saez-Rodriguez, Julio, Siegel, Anne, Guziołowski, Carito, Klamt, Steffen
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625540/
https://ncbi.nlm.nih.gov/pubmed/26510976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0733-7
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