NMR characterization of HIV-1 reverse transcriptase binding to various non-nucleoside reverse transcriptase inhibitors with different activities

Human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) is an important target for antiviral therapy against acquired immunodeficiency syndrome. However, the efficiency of available drugs is impaired most typically by drug-resistance mutations in this enzyme. In this study, we applied a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Thammaporn, Ratsupa, Yagi-Utsumi, Maho, Yamaguchi, Takumi, Boonsri, Pornthip, Saparpakorn, Patchreenart, Choowongkomon, Kiattawee, Techasakul, Supanna, Kato, Koichi, Hannongbua, Supa
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625163/
https://ncbi.nlm.nih.gov/pubmed/26510386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15806
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