Dipyridodiazepinone derivatives; synthesis and anti HIV-1 activity

Ten dipyridodiazepinone derivatives were synthesized and evaluated for their anti HIV-1 reverse transcriptase activity against wild-type and mutant type enzymes, K103N and Y181C. Two of them were found to be promising inhibitors for HIV-1 RT.

שמור ב:
מידע ביבליוגרפי
Main Authors: Khunnawutmanotham, Nisachon, Chimnoi, Nitirat, Thitithanyanont, Arunee, Saparpakorn, Patchreenart, Choowongkomon, Kiattawee, Pungpo, Pornpan, Hannongbua, Supa, Techasakul, Supanna
פורמט: Artigo
שפה:Inglês
יצא לאור: Beilstein-Institut 2009
נושאים:
Full Research Paper
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748688/
https://ncbi.nlm.nih.gov/pubmed/19777131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.5.36
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