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Dipyridodiazepinone derivatives; synthesis and anti HIV-1 activity
Ten dipyridodiazepinone derivatives were synthesized and evaluated for their anti HIV-1 reverse transcriptase activity against wild-type and mutant type enzymes, K103N and Y181C. Two of them were found to be promising inhibitors for HIV-1 RT.
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Beilstein-Institut
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748688/ https://ncbi.nlm.nih.gov/pubmed/19777131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.5.36 |
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