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Dynamic Enhancer Methylation - A Previously Unrecognized Switch for Tissue-Type Plasminogen Activator Expression

Tissue-type plasminogen activator (t-PA), which is synthesized in the endothelial cells lining the blood vessel walls, is a key player in the fibrinolytic system protecting the circulation against occluding thrombus formation. Although classical gene regulation has been quite extensively studied in...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Magnusson, Mia, Lu, Emma Xuchun, Larsson, Pia, Ulfhammer, Erik, Bergh, Niklas, Carén, Helena, Jern, Sverker
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4625093/
https://ncbi.nlm.nih.gov/pubmed/26509603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141805
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