Role of Histone Acetylation in the Stimulatory Effect of Valproic Acid on Vascular Endothelial Tissue-Type Plasminogen Activator Expression

AIMS: Stimulated release of tissue-type plasminogen activator (t-PA) is pivotal for an intravascular fibrinolytic response and protects the circulation from occluding thrombosis. Hence, an impaired t-PA production is associated with increased risk for atherothrombotic events. A pharmacological means...

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Autores principales: Larsson, Pia, Ulfhammer, Erik, Magnusson, Mia, Bergh, Niklas, Lunke, Sebastian, El-Osta, Assam, Medcalf, Robert L., Svensson, Per-Arne, Karlsson, Lena, Jern, Sverker
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282745/
https://ncbi.nlm.nih.gov/pubmed/22363677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031573
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