Histone Deacetylase Inhibition Enhances Tissue Plasminogen Activator Release Capacity in Atherosclerotic Man

The expression of the tissue plasminogen activator (t-PA) gene appears to be under epigenetic control and can be affected by histone deacetylation inhibition. The study aimed to test if histone deacetalyase inhibitor treatment lead to increased t-PA release or reduced exhaustion in t-PA release in r...

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Udgivet i:PLoS One
Main Authors: Svennerholm, Kristina, Haney, Michael, Biber, Björn, Ulfhammer, Erik, Saluveer, Ott, Larsson, Pia, Omerovic, Elmir, Jern, Sverker, Bergh, Niklas
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373842/
https://ncbi.nlm.nih.gov/pubmed/25807501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121196
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