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Histone Deacetylase Inhibition Enhances Tissue Plasminogen Activator Release Capacity in Atherosclerotic Man

The expression of the tissue plasminogen activator (t-PA) gene appears to be under epigenetic control and can be affected by histone deacetylation inhibition. The study aimed to test if histone deacetalyase inhibitor treatment lead to increased t-PA release or reduced exhaustion in t-PA release in r...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Svennerholm, Kristina, Haney, Michael, Biber, Björn, Ulfhammer, Erik, Saluveer, Ott, Larsson, Pia, Omerovic, Elmir, Jern, Sverker, Bergh, Niklas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373842/
https://ncbi.nlm.nih.gov/pubmed/25807501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121196
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