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High-Dose Nicotinamide Suppresses ROS Generation and Augments Population Expansion during CD8(+) T Cell Activation
During T cell activation, mitochondrial content increases to meet the high energy demand of rapid cell proliferation. With this increase, the level of reactive oxygen species (ROS) also increases and causes the rapid apoptotic death of activated cells, thereby facilitating T cell homeostasis. Nicoti...
Shranjeno v:
| izdano v: | Mol Cells |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Korean Society for Molecular and Cellular Biology
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4625074/ https://ncbi.nlm.nih.gov/pubmed/26442863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2015.0168 |
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