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Modulation of Mitochondrial Membrane Potential and ROS Generation by Nicotinamide in a Manner Independent of SIRT1 and Mitophagy
Nicotinamide (NAM) plays essential roles in physiology through facilitating NAD(+) redox homeostasis. Importantly, at high doses, it protects cells under oxidative stresses, and has shown therapeutic effectiveness in a variety of disease conditions. In our previous studies, NAM lowered reactive oxyg...
Shranjeno v:
| izdano v: | Mol Cells |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Korean Society for Molecular and Cellular Biology
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5547220/ https://ncbi.nlm.nih.gov/pubmed/28736426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2017.0081 |
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